Biotin Anti-Urokinase antibody,Abcam,AB49577

ATF is the amino terminal fragment of urokinase (uPA) corresponding to amino acid residues 1-135. uPA-ATF contains the growth factor like domain, which binds to the urokinase receptor, and the kringle domain which is involved in the induction of cell chemotaxis by urokinase. ATF inhibits the binding of urokinase to its receptor uPAR and acts as a broad inhibitor of cell migration.

Host

Rabbit

Reactivity

Human

Application

RIA, IP, ELISA, WB

Conjugate

Biotin

Platform ID

BAB292315237

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameBiotin Anti-Urokinase antibody
Cat. No.AB49577
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationBiotin
ApplicationRIA, IP, ELISA, WB
ClonalityPolyclonal
ImmunogenNative Full Length Protein corresponding to Human Urokinase-type plasminogen activator.
PurityAffinity purification Protein G
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.25% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Specifically cleaves the zymogen plasminogen to form the active enzyme plasmin. See full target information Urokinase-type plasminogen activator

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