Biotin Anti-alpha 1 Antitrypsin antibody,Abcam,AB48325

Host

Rabbit

Reactivity

Human

Application

ELISA, IP, WB, RIA

Conjugate

Biotin

Platform ID

BAB663604519

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameBiotin Anti-alpha 1 Antitrypsin antibody
Cat. No.AB48325
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationBiotin
ApplicationELISA, IP, WB, RIA
ClonalityPolyclonal
Concentration0.45 mg/mL Batch dependent concentration
ImmunogenNative Full Length Protein corresponding to Human SERPINA1.
PurityAffinity purification Protein G
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.25% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin. Irreversibly inhibits trypsin, chymotrypsin and plasminogen activator. The aberrant form inhibits insulin-induced NO synthesis in platelets, decreases coagulation time and has proteolytic activity against insulin and plasmin.. Short peptide from AAT. Reversible chymotrypsin inhibitor. It also inhibits elastase, but not trypsin. Its major physiological function is the protection of the lower respiratory tract against proteolytic destruction by human leukocyte elastase (HLE). See full target information SERPINA1

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