Biotin Anti-beta 2 Microglobulin antibody [B2M-02],Abcam,AB269365

Host

Mouse

Reactivity

Human

Application

Flow Cyt

Conjugate

Biotin

Platform ID

BAB163854399

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameBiotin Anti-beta 2 Microglobulin antibody [B2M-02]
Cat. No.AB269365
HostMouse
IsotypeIgG1
ReactivityHuman
ConjugationBiotin
ApplicationFlow Cyt
ClonalityMonoclonal
Clone NumberB2M-02
Concentration1 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human B2M. The exact immunogen used to generate this antibody is proprietary information.
PuritySize-exclusion chromatography
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.1% Sodium azide Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell surface (total protein levels do not change), probably leading to defects in class I antigen presentation (PubMed : 25356553). See full target information B2M

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.