Biotin Rabbit anti-Mouse CD25 mAb,ABclonal,A27356

Reactivity

Mouse

Application

FC

Conjugate

Biotin

Platform ID

BAB499483335

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

ABclonal

Contact

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Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameBiotin Rabbit anti-Mouse CD25 mAb
Cat. No.A27356
RRID#N/A
IsotypeIgG
ReactivityMouse
ConjugationBiotin
ApplicationFC
Working DilutionsFC:≤0.5 µg per million cells in 100 µl volume
Clone NumberARC54525
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at 2-8℃. Avoid freeze.; Buffer: PBS with 0.09% Sodium azide, 0.2% BSA, pH7.3.
Regulatory StatusResearch Use Only

Scientific Background

Enables interleukin-2 binding activity and interleukin-2 receptor activity. Acts upstream of or within several processes, including Notch signaling pathway; activation-induced cell death of T cells; and regulation of T cell proliferation. Located in external side of plasma membrane. Is expressed in bone marrow. Used to study Sjogren's syndrome and inflammatory bowel disease. Human ortholog(s) of this gene implicated in immunodeficiency 41; lymphopenia; multiple sclerosis; type 1 diabetes mellitus; and type 1 diabetes mellitus 10. Orthologous to human IL2RA (interleukin 2 receptor subunit alpha).

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