Biotin anti-beta-Amyloid, 1-16 Antibody anti-beta-Amyloid, 1-16 - 6E10,BioLegend,803007

This antibody is reactive to amino acid residue 1-16 of beta amyloid. The epitope lies within amino acids 3-8 of beta amyloid (EFRHDS).This antibody clone has been reported for use in immunohistochemistry of free-floating sections2,13.

Host

Mouse

Reactivity

Human

Application

IHC-P -Quality tested

Platform ID

BAB007974315

BioLegend

Headquarters

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Contact

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Product Specifications
Scientific Background

Specifications

NameBiotin anti-beta-Amyloid, 1-16 Antibody anti-beta-Amyloid, 1-16 - 6E10
Cat. No.803007
HostMouse
RRIDAB_2564657 (BioLegend Cat. No. 803007)AB_2564658 (BioLegend Cat. No. 803008)AB_2564656 (BioLegend Cat. No. 803009)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationIHC-P -Quality tested
ClonalityMonoclonal
Clone Number60000000000
Concentration1 mg/mL
Targetbeta-Amyloid 1-16
PurityThe antibody was purified by affinity chromatography.
FormulationPhosphate-buffered solution; no preservatives or carrier proteins.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C. Please note the storage condition for this antibody has been changed from -20°C to between 2°C and 8°C. You can also check your vial or your CoA to find the most accurate storage condition for this antibody.
Regulatory StatusResearch Use Only

Scientific Background

Alzheimer's disease is characterized by the accumulation of aggregated Aβ peptides in senile plaques and vascular deposits. Aβ peptides are derived from amyloid precursor proteins (APP) through sequential proteolytic cleavage of APP by β-secretases and γ-secretases generating diverse Aβ species. Aβ can aggregate to form soluble oligomeric species and insoluble fibrillar or amorphous assemblies. Some forms of the aggregated peptides are toxic to neurons.

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