Biotin anti-beta-Amyloid, 1-38 Antibody anti-beta-Amyloid, 1-38 - 7-14-4,BioLegend,808603

This antibody is effective in immunoblotting (WB), immunohistochemistry (IHC), and ELISA.*Expected MW: 4 kDWB Positive Control: Alzheimer's Brain LysateIHC Positive Control: Alzheimer's Brain TissueThis antibody is reactive to the C-terminus of beta amyloid and is specific for the isoform that ends at the 38th amino acid.

Host

Rabbit

Reactivity

Human

Application

ELISA, WB, IHCICC - Reported in the literature, not verified in house

Platform ID

BAB758549039

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Product Specifications
Scientific Background

Specifications

NameBiotin anti-beta-Amyloid, 1-38 Antibody anti-beta-Amyloid, 1-38 - 7-14-4
Cat. No.808603
HostRabbit
RRIDAB_2564746 (BioLegend Cat. No. 808603)
IsotypeRabbit Ig
ReactivityHuman
ApplicationELISA, WB, IHCICC - Reported in the literature, not verified in house
ClonalityMonoclonal
Clone Number7-14-4
Concentration1 mg/ml
Targetbeta-Amyloid 1-38
PurityThe antibody was purified by affinity chromatography.
FormulationPhosphate-buffered solution.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C. Please note the storage condition for this antibody has been changed from -20°C to between 2°C and 8°C. You can also check your vial or your CoA to find the most accurate storage condition for this antibody.
Regulatory StatusResearch Use Only

Scientific Background

Soluble Aβ (Amyloid-beta, beta-amyloid, or Abeta) peptides, 36 to 43 amino acids in length, are natural proteolytic cleavage products of amyloid precursor protein (APP). However, soluble abnormally aggregated Aβ species are associated with Alzheimer's disease (AD), can be toxic to neurons, and insoluble Aβ aggregates are the main component of cerebral amyloid plaques, which are a pathological hallmark of AD.

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