Biotin anti-human CCL5 RANTES Antibody anti-CCL5 - Poly5197,BioLegend,519703
ELISA Detection:The biotinylated Poly5197 antibody is useful as the detection antibody in a sandwich ELISA assay, when used in conjunction with the purified antibody J047C5 (Cat. No.526402) as the capture antibody and recombinant human CCL5 (RANTES) (Cat. No.580209) as the standard.Note:For testing human CCL5 in serum, plasma or cell culture supernatant, LEGEND MAX™ Human CCL5 (RANTES) ELISA Kit with Pre-coated Plates (Cat. No. 440807 & 440808) are specially developed and recommended.
Host
Goat
Reactivity
Human
Application
ELISA Detection - Quality tested
Platform ID
BAB267283580
BioLegend
Contact
Tel: 1-858-455-9588
Fax: +49 (4131) 7023913
Email:
Specifications
Scientific Background
CCL5 (RANTES), also known as CCL5, is a 7.8 kD member of the CC family of chemokines, which is expressed in T cells and monocytes/macrophages. RANTES is strongly chemotactic for monocytes/macrophages, memory T cells, eosinophils, and induces histamine release from basophils. In a solution, RANTES can form high molecular weight aggregates that exhibit dissimilar biological activities to its dimeric form. The aggregates cause T cell and neutrophil activation while promoting HIV infection, whereas the dimeric form exhibits RANTES-induced chemotaxis and inhibits HIV infection. As T cells become activated, RANTES secretion appears to decrease.
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
Please provide the required information below so that we can quickly source your products.