Biotin anti-human CD275 B7-H2, ICOSL Antibody anti-CD275 - 2D3,BioLegend,309406
Host
Mouse
Reactivity
Human
Application
FC - Quality tested
Platform ID
BAB427051912
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NameBiotin anti-human CD275 B7-H2, ICOSL Antibody anti-CD275 - 2D3
Cat. No.309406
HostMouse
RRIDAB_528729 (BioLegend Cat. No. 309406)
IsotypeMouse IgG2b, κ
ReactivityHuman
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone Number2D3
Concentration0.5 mg/ml
TargetCD275
ImmunogenHuman B7H2-mIg fusion protein
PurityThe antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
B7-H2, a member of the B7 family and the immunoglobulin superfamily, is a 40 kD protein also known as B7RP-1, B7h, B7-H2, GL50 and ICOS Ligand. Human B7-H2 is expressed by B lymphocytes, activated monocytes/macrophages, and dendritic cells. B7-H2 binds to a CD28-like receptor, inducible costimulator molecule (ICOS, AILIM, CRP-1), which is expressed by activated T cells. The interaction of ICOS with B7-H2 plays an important role in the T cell costimulation pathway.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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