Biotin anti-human IL-1 RA Antibody anti-IL-1RA - Poly5095,BioLegend,509502

ELISA Detection:The biotinylated Poly5095 antibody is useful as the detection antibody in a sandwich ELISA assay, when used in conjunction with the purified JK1RA-1 (Cat. No. 509902) antibody as the capture antibody.This product may contain other non-IgG subtypes.

Host

Rabbit

Reactivity

Human

Application

ELISA Detection

Platform ID

BAB153304523

BioLegend

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Contact

Tel: 1-858-455-9588
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Product Specifications
Scientific Background

Specifications

NameBiotin anti-human IL-1 RA Antibody anti-IL-1RA - Poly5095
Cat. No.509502
HostRabbit
RRIDAB_315540 (BioLegend Cat. No. 509502)
IsotypeRabbit Polyclonal IgG
ReactivityHuman
ApplicationELISA Detection
ClonalityPolyclonal
Clone NumberPoly5095
Concentration0.5 mg/ml
TargetIL-1RA
ImmunogenRecombinant human IL-1 receptor antagonist
PurityThe antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

Interleukin-1 receptor antagonist (IL-1RA) is composed of three isoforms, one secreted (sIL-1Rα/IL-1Rα1), two intracellular (IL-1Rα2/IL-1Rα3) and produced by monocytes, tissue macrophages, Langerhans cells, dendritic cells, T and B cells, natural killer (NK) cells, large granular lymphocytes (LGL), vascular endothelium, smooth muscle, fibroblasts, thymic epithelia, astrocytes, microglia, glioma cells, keratinocytes, and chondrocytes. It is upregulated by IL-1β, IL-4, IL-6 and downregulated by glucocorticoids. The Poly5095 polyclonal antibody reacts with human interleukin-1 receptor antagonist (IL-1RA).

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