Biotin anti-human beta2-microglobulin Antibody anti-beta2-microglobulin - 2M2,BioLegend,316308
Additional reported applications (for the relevant formats) include: Western blotting, and ELISA.
Host
Mouse
Reactivity
Human
Application
FC - Quality tested
Platform ID
BAB463311970
BioLegend
Contact
Tel: 1-858-455-9588
Fax: +49 (4131) 7023913
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Product Specifications
Scientific Background
Specifications
NameBiotin anti-human beta2-microglobulin Antibody anti-beta2-microglobulin - 2M2
Cat. No.316308
HostMouse
RRIDAB_493689 (BioLegend Cat. No. 316308)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone Number2M2
Concentration0.5 mg/ml
Targetbeta2-microglobulin
ImmunogenPurified human β2-microglobulin
PurityThe antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
β2-microglobulin (β2M) is a 12 kD nonpolymorphic Ig like protein. It is a non-membrane-anchored glycoprotein and is noncovalently associated with 39-44 kD polymorphic heavy chains of MHC class I molecules to form HLA class I antigen complex. In association with HLA class I, β2M is expressed on all leukocytes, platelets, endothelial cells, and epithelial cells. β2M plays an essential role both in governing MHC class I molecules stability and in promoting antigen binding and presenting the antigen to CD3/TCR complex of CD8+T cells.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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