Biotin anti-mouse CD137 Antibody anti-CD137 - 17B5,BioLegend,106104
Additional reported applications (for the relevant formats) include:in vitroblocking of 4-1BB-mediated T cell proliferation2. The LEAF™ purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 106108).
Host
Syrian Hamster
Reactivity
Mouse
Application
FC - Quality tested
Platform ID
BAB043068726
BioLegend
Contact
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Product Specifications
Scientific Background
Specifications
NameBiotin anti-mouse CD137 Antibody anti-CD137 - 17B5
Cat. No.106104
HostSyrian Hamster
RRIDAB_313240 (BioLegend Cat. No. 106103)AB_313241 (BioLegend Cat. No. 106104)
IsotypeSyrian Hamster IgG
ReactivityMouse
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone Number17B5
Concentration0.5 mg/ml
TargetCD137
PurityThe antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD137 is a 39 kD TNF-receptor superfamily member also known as 4-1BB, TNFRSF9, Ly-63, and ILA (Induced by Lymphocyte Activation). CD137 is expressed as monomers, dimers, and tetramers on activated T and B cells. Interaction of CD137 with its ligand, 4-1BBL (CD137L), is important in T-B cell costimulation. The 17B5 antibody has been reported to block 4-1BBL costimulated T cell proliferation.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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