Biotin anti-mouse CD198 CCR8 Antibody anti-CD498 - SA214G2,BioLegend,150316

Host

Rat

Reactivity

Mouse

Application

FC -Quality tested

Platform ID

BAB950967898

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

Email:

Product Specifications
Scientific Background

Specifications

NameBiotin anti-mouse CD198 CCR8 Antibody anti-CD498 - SA214G2
Cat. No.150316
HostRat
RRIDAB_2716237 (BioLegend Cat. No. 150316)
IsotypeRat IgG2b, κ
ReactivityMouse
ApplicationFC -Quality tested
ClonalityMonoclonal
Clone NumberSA214G2
Concentration0.5 mg/ml
TargetCD198
ImmunogenMouse CD198 (CCR8)-transfected cells
PurityThe antibody was purified by affinity chromatography and conjugated with biotin under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

C-C chemokine receptor type 8 (CCR8) CD198, is a 41 kD G-protein coupled receptor with 7 transmembrane regions. CCR8 is expressed by a subset of thymocytes, Tregs, NKT and Th2-polarized cells, a subset of macrophages, monocytes, and monocyte-derived dendritic cells. CCR8 mediates chemotaxis toward its ligand CCL1, and is involved in apoptosis of thymocytes.

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