Biotin anti-mouse CD21/CD35 CR2/CR1 Antibody anti-CD21/35 - 7E9,BioLegend,123405

Host

Rat

Reactivity

Mouse

Application

FC - Quality tested

Platform ID

BAB197117276

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

Email:

Product Specifications
Scientific Background

Specifications

NameBiotin anti-mouse CD21/CD35 CR2/CR1 Antibody anti-CD21/35 - 7E9
Cat. No.123405
HostRat
RRIDAB_940399 (BioLegend Cat. No. 123405)AB_940401 (BioLegend Cat. No. 123406)
IsotypeRat IgG2a, κ
ReactivityMouse
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone Number7000000000
Concentration0.5 mg/ml
TargetCD21/CD35
ImmunogenCD35/CFA
PurityThe antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

CD21, also known as CR2 (complement receptor 2) and C3d receptor, binds C3d and iC3b. It is also a receptor of Epstein-Barr virus. CD35, also known as CR1, binds C3b, iC3b, C4b, and iC4b. CD21/CD35 is primarily expressed on B lymphocytes, mast cells, follicular dendritic cells, macrophages, and activated granulocytes. CD21/CD35 forms part of the B-cell antigen receptor complex with CD19 and CD81 and is involved in signal transduction.

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