Biotin anti-mouse CD254 TRANCE, RANKL Antibody anti-CD254 - IK22/5,BioLegend,510003
The IK22/5 antibody has been reported to block the binding of RANK ligand-Fc to RANK. Additional reported applications (for the relevant formats) include: immunoprecipitation2, Western blotting2, and blocking of ligand binding1,2,4. The Ultra-LEAF™ purified antibody (Endotoxin <0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 510009-510014).
Host
Rat
Reactivity
Mouse
Application
FC - Quality tested
Platform ID
BAB300978663
BioLegend
Contact
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Product Specifications
Scientific Background
Specifications
NameBiotin anti-mouse CD254 TRANCE, RANKL Antibody anti-CD254 - IK22/5
Cat. No.510003
HostRat
RRIDAB_315551 (BioLegend Cat. No. 510003)AB_315552 (BioLegend Cat. No. 510004)
IsotypeRat IgG2a, κ
ReactivityMouse
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberIK22/5
Concentration0.5 mg/ml
TargetCD254
ImmunogenNSO-derived recombinant mouse TRANCE
PurityThe antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD254 is a 19 kD TNF superfamily member also known as TRANCE (TNF-related activation induced cytokine), RANK ligand, RANKL, TNFSF11, OPGL, and ODF. TRANCE is expressed on activated T cells and osteoclasts and has been implicated in the regulation of T cell and dendritic cell interactions as well as osteoclast differentiation.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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