Biotin anti-mouse CD279 PD-1 Antibody anti-CD279 - RMP1-30,BioLegend,109105
The RMP1-30 antibody does not block the binding of PD-1 to B7-H1 and B7-DC1.
Host
Rat
Reactivity
Mouse
Application
FC - Quality tested
Platform ID
BAB461324189
BioLegend
Contact
Tel: 1-858-455-9588
Fax: +49 (4131) 7023913
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Product Specifications
Scientific Background
Specifications
NameBiotin anti-mouse CD279 PD-1 Antibody anti-CD279 - RMP1-30
Cat. No.109105
HostRat
RRIDAB_313422 (BioLegend Cat. No. 109105)AB_313423 (BioLegend Cat. No. 109106)
IsotypeRat IgG2b, κ
ReactivityMouse
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberRMP1-30
Concentration0.5 mg/ml
TargetCD279
ImmunogenMouse PD-1 transfected BHK cells
PurityThe antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD279 is a 50-55 kD immunoglobulin superfamily member also known as programmed death-1 (PD-1). PD-1 is expressed on a subset of CD4-CD8-thymocytes and on activated T and B cells. PD-1 is thought to be involved in lymphocyte clonal selection and peripheral tolerance. The PD-1 ligands, PD-L1 (also known as B7-H1) and PD-L2 (B7-DC), are members of the B7 immunoglobulin superfamily.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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