Biotin anti-mouse / rat IL-1beta Antibody anti-IL-1beta - B122,BioLegend,503505
ELISA or ELISPOT Capture3:The purified B122 antibody is useful as the capture antibody in a mouse IL-1ß sandwich ELISA or ELISPOT assay, when used in conjunction with the biotinylated Poly5158 antibody (Cat. No. 515801) as the detecting antibody. The LEAF™ purified antibody is suggested for ELISPOT capture.Certain formats of clone B122 have been reported forin vitroneutralization of IL-1ß bioactivity1,in vivocytokine depletion5, immunohistochemical staining of frozen sections6, Western blotting7, and the study of endotoxin shock8.
Host
Armenian Hamster
Reactivity
Mouse, Rat
Application
ELISA -Quality tested
Platform ID
BAB331675186
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NameBiotin anti-mouse / rat IL-1beta Antibody anti-IL-1beta - B122
Cat. No.503505
HostArmenian Hamster
RRIDAB_2295906 (BioLegend Cat. No. 503505)
IsotypeArmenian Hamster IgG
ReactivityMouse, Rat
ApplicationELISA -Quality tested
ClonalityMonoclonal
Clone NumberB122
Concentration0.5 mg/ml
TargetIL-1beta
ImmunogenE. coli-expressed, recombinant mouse IL-1β
PurityThe antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
IL-1 refers to two proteins, IL-1α and IL-1β which are the products of distinct genes, but which are recognized by the same cell surface receptors. IL-1β is a potent immuno-modulator which mediates a wide range of immune and inflammatory responses including the activation of B and T cells. The B122 antibody reacts with the precursor and mature secreted forms of mouse IL-1β. This antibody also recognizes rat IL-1β. The B122 antibody can neutralize the bioactivity of natural or recombinant IL-1β.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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