Biotin anti-mouse/rat beta-Amyloid, 1-16 Antibody anti-beta-Amyloid, 1-16 - M3.2,BioLegend,805704
Clone M3.2 recognizes a rodent sequence of Aß, ß-CTF, sAPP-a, and full length APP. Clone 3.2 has negligible cross reactivity with human isoforms of APP and beta amyloid.
Host
Mouse
Reactivity
Mouse, Rat
Application
WB - Quality testedICC - Reported in the literature, not verified in houseELISA
Platform ID
BAB061048827

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Product Specifications
Scientific Background
Specifications
NameBiotin anti-mouse/rat beta-Amyloid, 1-16 Antibody anti-beta-Amyloid, 1-16 - M3.2
Cat. No.805704
HostMouse
RRIDAB_2564984 (BioLegend Cat. No. 805703)AB_2564983 (BioLegend Cat. No. 805704)
IsotypeMouse IgG1, κ
ReactivityMouse, Rat
ApplicationWB - Quality testedICC - Reported in the literature, not verified in houseELISA
ClonalityMonoclonal
Clone NumberM3.2
Concentration1 mg/mL
Targetbeta-Amyloid 1-16
ImmunogenThe epitope has been determined to be within residues 10-15 of murine Aβ.
PurityThe antibody was purified by affinity chromatography.
FormulationPhosphate-buffered solution; no preservatives or carrier proteins.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C. Please note the storage condition for this antibody has been changed from -20°C to between 2°C and 8°C. You can also check your vial or your CoA to find the most accurate storage condition for this antibody.
Regulatory StatusResearch Use Only
Scientific Background
Alzheimer's disease is characterized by the accumulation of aggregated Aβ peptides in senile plaques and vascular deposits. Aβ peptides are derived from amyloid precursor proteins (APP) through sequential proteolytic cleavage of APP by β-secretases and γ-secretases generating diverse Aβ species. Aβ can aggregate to form soluble oligomeric species and insoluble fibrillar or amorphous assemblies. Some forms of the aggregated peptides are toxic to neurons.
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