Biotinylated Anti-Human CD3 Antibody, Mouse F(ab')2, His,AvitagTM (Clone: OKT3), premium grade,Acro Biosystems,CDE-CV81G0

Biotinylated Anti-Human CD3 Antibody, Mouse F(ab')2, His,Avitag (Clone: OKT3), premium grade (CDE-CV81G0) is an F(ab')2 fragment-only antibody recombinantly expressed from HEK293 cells. It is produced under our rigorous quality control system that incorporates a comprehensive set of tests including sterility and endotoxin tests. Product performance is carefully validated and tested for compatibility for cell culture use or any other applications in the early preclinical stage. When ready to transition into later clinical phases, we also offer a custom GMP protein service that tailors to your needs. We will work with you to customize and develop a GMP-grade product in accordance with your requests that also meets the requirements for raw and ancillary materials use in cell manufacturing of cell-based therapies.

Conjugate

Biotin

Platform ID

BAB840763120

Acro Biosystems

Headquarters

1 Innovation Way Newark, Delaware 19711 US

Contact

Tel: +1 800-810-0816
Fax:

Product Specifications

Specifications

NameBiotinylated Anti-Human CD3 Antibody, Mouse F(ab')2, His,AvitagTM (Clone: OKT3), premium grade
Cat. No.CDE-CV81G0
ConjugationBiotin
Purity>95% as determined by SDS-PAGE. >95% as determined by SEC-HPLC.
FormulationSupplied as 0.2 μm filtered solution in PBS, pH7.4 with trehalose as protectant. Contact us for customized product form or formulation.
StorageCD3e molecule, epsilon is also known as CD3E, is a T-cell surface single-pass type I membrane glycoprotein. CD3E contains 1 Ig-like (immunoglobulin-like) domain and 1 ITAM domain. CD3E, together with CD3-gamma, CD3-delta and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. CD3E plays an essential role in T-cell development, and defects in CD3E gene cause severe immunodeficiency. CD3E gene has also been linked to a susceptibility to type I diabetes in women. CD3E has been shown to interact with TOP2B, CD3EAP and NCK2.

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