Biotinylated Monoclonal Anti-PBD Antibody, Rabbit IgG (1M1F9),Acro Biosystems,PBD-BLMY2212
Biotinylated Monoclonal Anti-PBD Antibody, Rabbit IgG (1M1F9) is a Rabbit monoclonal antibody recombinantly expressed from HEK293 cells.
Application
ELISA
Conjugate
Biotin
Platform ID
BAB092187436
Acro Biosystems
Contact
Tel: +1 800-810-0816
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Product Specifications
Specifications
NameBiotinylated Monoclonal Anti-PBD Antibody, Rabbit IgG (1M1F9)
Cat. No.PBD-BLMY2212
IsotypeRabbit IgG | Rabbit Kappa
ConjugationBiotin
ApplicationELISA
Working Dilutions0.5-125 ng/mL
Clone Number1M1F9
ImmunogenPBD-BSA
FormulationLyophilized from a 0.22 μm-filtered solution in PBS (pH 7.4), with trehalose as protectant.
Please contact us for customized product forms or formulations.
ReconstitutionPlease refer to the Certificate of Analysis (CoA) for specific instructions.
For best performance, we strongly recommend following the reconstitution protocol provided in the CoA.
StoragePyrrolobenzodiazepine (PBD) dimer, is a new generation of cytotoxic payload used in antibody-drug conjugates (ADCs). The PBD dimer binds to the minor groove of DNA to form effective cytotoxic DNA interstrand crosslinks, which can block cell division and kill cancer cells. This mechanism of action utilizes a completely different cellular target from that of tubulin inhibitors, as well as a different DNA damage pattern from other DNA-targeting payloads. Anti-PBD antibody is a rabbit monoclonal antibody specially reacts with PBD, which is more sensitive than mouse antibody. The anti-PBD antibody is a useful reagent in PK assay to determine conjugated antibodies.
Category Paths
- Products>Anti-payload Antibodies
- Products>Primary Antibodies>Monoclonal Antibodies
- Products>Primary Antibodies>Conjugated Antibodies
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