Bmi1 antibody,Genetex,GTX114008

Host

Rabbit

Reactivity

Human, Mouse, Cat, Dog

Application

WB ICC/IF IHC-P IP

Conjugate

Unconjugated

Platform ID

BAB257144771

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameBmi1 antibody
Cat. No.GTX114008
Gene ID (Entrez)648
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Cat, Dog
ConjugationUnconjugated
ApplicationWB ICC/IF IHC-P IP
ClonalityPolyclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
TargetBMI1
ImmunogenRecombinant protein encompassing a sequence within the center region of human Bmi1. The exact sequence is proprietary.
PurityPurified by antigen-affinity chromatography.
Appearance/FormLiquid
Formulation0.1M Tris, 0.1M Glycine, 20% Glycerol,0.01% Thimerosal
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.

Synonyms

BMI1 proto-oncogene, polycomb ring finger , FLVI2/BMI1 , PCGF4 , RNF51 , flvi-2/bmi-1

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.