Brilliant Violet 421 anti-human CD107b LAMP-2 Antibody anti-Cd107b - H4B4,BioLegend,354308
Additional reported applications (for the relevant formats) include: immunohistochemical staining of frozen glomeruli2and immunofluorescent staining of neutrophils2,3.This antibody is specific to human LAMP-2. Positive control: Hela cells; LAMP-2 molecular weight appears to be at ~110 kDa on the gel due to high glycosylation.
Host
Mouse
Reactivity
Human
Application
ICFC -Quality testedIHC-P -Verified
Platform ID
BAB477627624
BioLegend
Contact
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Product Specifications
Scientific Background
Specifications
NameBrilliant Violet 421 anti-human CD107b LAMP-2 Antibody anti-Cd107b - H4B4
Cat. No.354308
HostMouse
RRIDAB_2721513 (BioLegend Cat. No. 354308)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationICFC -Quality testedIHC-P -Verified
ClonalityMonoclonal
Clone NumberH4B4
Concentration0.2 mg/mL
TargetCD107b
ImmunogenAdult human adherent spleen cells
PurityThe antibody was purified by affinity chromatography and conjugated with Brilliant Violet 421™ under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA).
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD107b, also known as LAMP-2, is a 105 kD, highly gylcosylated, type I transmembrane protein. CD107b is expressed in lysosomal/endosomal membranes in nearly all cells, and on the surface of activated platelets, activated lymphocytes and some tumor cell lines. LAMP-2 is known to have roles in cell adhesion and cellular homeostasis, including autophagocytosis and antigen presentation.
Category Paths
- Products>Primary Antibodies>IHC Antibodies
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