Brilliant Violet 421 anti-human CD11c Antibody anti-CD11c - Bu15,BioLegend,337226
Clone Bu15 has a different binding epitope than clone 3.9. The binding of Bu15 with CD11c is divalent cation independent. Additional reported applications (for the relevant formats of this clone) include: inhibition of CD11c mediated adhesion and stimulation of chemokine production by monocytes.
Host
Mouse
Reactivity
Human
Application
FC - Quality tested
Platform ID
BAB711460388
BioLegend
Contact
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Product Specifications
Scientific Background
Specifications
NameBrilliant Violet 421 anti-human CD11c Antibody anti-CD11c - Bu15
Cat. No.337226
HostMouse
RRIDAB_2564484 (BioLegend Cat. No. 337225)AB_2564485 (BioLegend Cat. No. 337226)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberBu15
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetCD11c
PurityThe antibody was purified by affinity chromatography and conjugated with Brilliant Violet 421™ under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA).
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD11c is a 145-150 kD type I transmembrane glycoprotein also known as integrin αxand CR4. CD11c non-covalently associates with integrin β2(CD18) and is expressed on monocytes/macrophages, dendritic cells, granulocytes, NK cells, and subsets of T and B cells. CD11c has been reported to play a role in adhesion and CTL killing through its interactions with fibrinogen, CD54, and iC3b.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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