Brilliant Violet 421 anti-human CD335 NKp46 Antibody anti-CD335 - 9E2,BioLegend,331913
Clone 9E2 has been shown to block NK activation through NKp46.6
Host
Mouse
Reactivity
Human
Application
FC - Quality tested
Platform ID
BAB450540632
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NameBrilliant Violet 421 anti-human CD335 NKp46 Antibody anti-CD335 - 9E2
Cat. No.331913
HostMouse
RRIDAB_10916529 (BioLegend Cat. No. 331913)AB_2563853 (BioLegend Cat. No. 331914)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone Number900
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetCD335
ImmunogenNKp46-Fc fusion protein
PurityThe antibody was purified by affinity chromatography and conjugated with Brilliant Violet 421™ under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA).
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD335, also known as NKp46, is a member of the natural cytotoxicity receptor (NCR) family which triggers cytotoxicity in NK cells. CD335 is directly involved in target cell recognition and lysis, and is exclusively expressed on CD3-CD56+NK cells, suggesting it is a universal marker for NK cells. NKp46, along with NKp30 and NKp44, is referred to as a natural cytoxicity receptor (NCR) and plays a very important role in killing virus-infected tumor cells and MHC-class I-unprotected cells.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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