Brilliant Violet 421™ anti-human CD7 Antibody, CD7, A20153E,BioLegend,385811
Clone A20153E can completely block binding of clone 4H9-CD7 and partially blocks binding of clone CD7-6B7 on target cells.
Host
Mouse
Reactivity
Human
Application
FC - Quality tested
Platform ID
BAB678053902
BioLegend
Contact
Tel: 1-858-455-9588
Fax: +49 (4131) 7023913
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Product Specifications
Scientific Background
Specifications
NameBrilliant Violet 421™ anti-human CD7 Antibody, CD7, A20153E
Cat. No.385811
HostMouse
RRIDAB_3662284 (BioLegend Cat. No. 385811)AB_3662284 (BioLegend Cat. No. 385812)
IsotypeMouse IgG2b, κ
ReactivityHuman
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberA20153E
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetCD7
ImmunogenHuman CD7 recombinant protein
PurityThe antibody was purified by affinity chromatography and conjugated with Brilliant Violet 421™ under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD7 is a 40 kD type I transmembrane glycoprotein also known as gp40. It is a member of the immunoglobulin superfamily found on T cells, NK cells, thymocytes, hematopoietic progenitors, and monocytes (weakly). CD7 is also expressed on acute lymphocytic leukemia (ALL) and some acute myeloid leukemia (AML) cells. CD7 crosslinking induces a calcium flux in T lymphocytes, presumably as a result of cytoplasmic domain association with PI3-kinase. CD7 costimulation can induce cytokine secretion and modulate cellular adhesion.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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