Brilliant Violet 421 anti-human GPR15 Antibody - anti-GPR15 - SA302A10,BioLegend,373008
Host
Mouse
Reactivity
Human
Application
FC -Quality tested
Platform ID
BAB201892454
BioLegend
Contact
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Product Specifications
Scientific Background
Specifications
NameBrilliant Violet 421 anti-human GPR15 Antibody - anti-GPR15 - SA302A10
Cat. No.373008
HostMouse
RRIDAB_2650858 (BioLegend Cat. No. 373007)AB_2650859 (BioLegend Cat. No. 373008)
IsotypeMouse IgG2a, κ
ReactivityHuman
ApplicationFC -Quality tested
ClonalityMonoclonal
Clone NumberSA302A10
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetGPR15
ImmunogenHuman GPR15-transfected cells.
PurityThe antibody was purified by affinity chromatography and conjugated with Brilliant Violet 421™ under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA).
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
GPR15, also known as BOB, is a G-protein coupled receptor with 7 transmembrane regions, that is present on the cell surface as an homotrimer. Its ligand, GPR15L, was recently identified. It acts as receptor for human immunodeficiency virus type 1 and 2. GPR15 is expressed by effector T cells and subsets of memory T cells, and is involved in the recruitment of proinflammatory CD4+T cells responsible of the pathogenesis in colitis. It is upregulated on monocytes and neutrophils in the synovia of patients with RA.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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