Brilliant Violet 421 anti-human KLRG1 MAFA Antibody anti-KLRG1 - 14C2A07,BioLegend,368603
Host
Mouse
Reactivity
Human
Application
FC - Quality tested
Platform ID
BAB667758846
BioLegend
Contact
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Product Specifications
Scientific Background
Specifications
NameBrilliant Violet 421 anti-human KLRG1 MAFA Antibody anti-KLRG1 - 14C2A07
Cat. No.368603
HostMouse
RRIDAB_2566592 (BioLegend Cat. No. 368603)AB_2566593 (BioLegend Cat. No. 368604)
IsotypeMouse IgG2a, κ
ReactivityHuman
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone Number14C2A07
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetKLRG1
ImmunogenHuman KLRG1-transfected cells.
PurityThe antibody was purified by affinity chromatography and conjugated with Brilliant Violet 421™ under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA).
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
Killer cell lectin-like receptor subfamily G member (KLRG1) is a 30 kD, type II membrane glycoprotein with one C-type lectin domain and one immunoreceptor tyrosine-based inhibitory motif (ITIM). KLRG1 is expressed by subsets of natural killer cells (NKs) and effector and memory T cells. It inhibits cell activation and proliferation and is also a marker of T cell senescence. The binding of KLRG1 to E-, N-, or R- cadherins blocks phosphorylation of AKT and increases the expression of cell cycle inhibitors.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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