Brilliant Violet 421 anti-mouse CD11c Antibody anti-CD11c - N418,BioLegend,117343
Additional reported applications (for the relevant formats) include: immunoprecipitation3, immunohistochemical staining of acetone-fixed frozen sections3, immunofluorescence microscopy5, 9(Alexa Fluor® 488 conjugated N418 was used for IHC in frozen sections10), and spatial biology (IBEX)22,23.
Host
Armenian Hamster
Reactivity
Mouse
Application
FC - Quality testedIHC - Verified
Platform ID
BAB134124998
BioLegend
Contact
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Product Specifications
Scientific Background
Specifications
NameBrilliant Violet 421 anti-mouse CD11c Antibody anti-CD11c - N418
Cat. No.117343
HostArmenian Hamster
RRIDAB_10897814 (BioLegend Cat. No. 117329)AB_2563099 (BioLegend Cat. No. 117343)AB_11219593 (BioLegend Cat. No. 117330)
IsotypeArmenian Hamster IgG
ReactivityMouse
ApplicationFC - Quality testedIHC - Verified
ClonalityMonoclonal
Clone NumberN418
Concentrationµg sizes: 0.2 mg/mLµL sizes: lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetCD11c
ImmunogenMouse spleen dendritic cells
PurityThe antibody was purified by affinity chromatography and conjugated with Brilliant Violet 421™ under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA).
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD11c is a 150 kD glycoprotein also known as αXintegrin, CR4, and p150. CD11c forms a αXβ2heterodimer with β2integrin (CD18). It is primarily expressed on dendritic cells, NK cells, a subset of intestinal intraepithelial lymphocytes (IEL), and some activated T cells. The αXβ2integrin plays an important role in cell-cell contact by binding its ligands: iC3b, fibrinogen, and CD54.
Category Paths
- Products>Primary Antibodies>IHC Antibodies
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