Brilliant Violet 421 anti-mouse CD185 CXCR5 Antibody anti-CD185 - L138D7,BioLegend,145512
Clone L138D7 staining works optimally at room temperature or 4°C. Unlike other chemokine receptor antibodies, avoid using L138D7 at 37°C.
Host
Rat
Reactivity
Mouse
Application
FC - Quality tested
Platform ID
BAB121119979
BioLegend
Contact
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Product Specifications
Scientific Background
Specifications
NameBrilliant Violet 421 anti-mouse CD185 CXCR5 Antibody anti-CD185 - L138D7
Cat. No.145512
HostRat
RRIDAB_2562127 (BioLegend Cat. No. 145511)AB_2562128 (BioLegend Cat. No. 145512)
IsotypeRat IgG2b, κ
ReactivityMouse
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberL138D7
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetCD185
ImmunogenmCXCR5-transfected cells
PurityThe antibody was purified by affinity chromatography and conjugated with Brilliant Violet 421™ under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA).
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD185 is also known as CXCR5. It is the receptor for chemokine CXCL13/BLC, which is chemotactic for B cells. CXCR5 is expressed on B cells and a subset of T cells in the spleen, neuronal tissue, lymph nodes, and bone marrow. It is important for migration of B cells into the B cell follicles of the spleen and Peyer’s patches. Follicular helper T cells (Tfh) also express CXCR5 and the ability of these cells to migrate to the lymph node is modulated by the balanced expression of CCR7 and CXCR5.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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