Brilliant Violet 421™ anti-mouse CD28 Antibody, CD28, E18,BioLegend,122023
Additional reported applications (for the relevant formats) include:in vitrocostimulation of T and NK cells1,in vitroblocking of allogeneic mixed leukocyte response and inhibition of MHC-unrestricted CTL cytotoxicity, andin vitroinduction of thymocyte differentiation. The LEAF™ purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 122004).
Host
Mouse
Reactivity
Mouse
Application
FC - Quality tested
Platform ID
BAB221005804
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NameBrilliant Violet 421™ anti-mouse CD28 Antibody, CD28, E18
Cat. No.122023
HostMouse
RRIDAB_3674981 (BioLegend Cat. No. 122023)
IsotypeMouse IgG2b, κ
ReactivityMouse
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberE18
Concentration0.2 mg/mL
TargetCD28
ImmunogenA20 cells and recombinant mCD28Ig
PurityThe antibody was purified by affinity chromatography and conjugated with Brilliant Violet 421™ under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD28 is a 44 kD glycoprotein, also known as Tp44 or T44. It is a member of the Ig superfamily, expressed on thymocytes, most peripheral T cells, and NK cells. In association with CD80 (B7-1) and CD86 (B7-2), CD28 acts as the second signal for T and NK cell activation and proliferation. The E18 antibody blocks the binding of 37.51 antibody to CD28 and costimulates T cell activation and proliferation.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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