Brilliant Violet 421 anti-mouse CD28 Antibody anti-CD28 - 37.51,BioLegend,102127
Additional reported applications (for the relevant formats) include: immunoprecipitation1,in vitrocostimulation of T and NK cells1,in vitroblocking of allogeneic mixed leukocyte response and inhibition of MHC-unrestricted CTL cytotoxicity3,4,in vitroinduction of thymocyte differentiation2,5-9,11, and immunohistochemical staining of acetone-fixed frozen sections. Forin vivostudies or highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) (Cat. No. 102116).
Host
Syrian Hamster
Reactivity
Mouse
Application
FC - Quality tested
Platform ID
BAB868818613
BioLegend
Contact
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Product Specifications
Scientific Background
Specifications
NameBrilliant Violet 421 anti-mouse CD28 Antibody anti-CD28 - 37.51
Cat. No.102127
HostSyrian Hamster
RRIDAB_2650628 (BioLegend Cat. No. 102127)
IsotypeSyrian Hamster IgG
ReactivityMouse
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone Number37.51
Concentration0.2 mg/ml
TargetCD28
ImmunogenC57BL/6 mouse T-cell lymphoma EL-4
PurityThe antibody was purified by affinity chromatography and conjugated with Brilliant Violet 421™ under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA).
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD28 is a 44 kD glycoprotein, also known as Tp44 or T44. It is a member of the Ig superfamily, expressed on thymocytes, most peripheral T cells, and NK cells. In association with CD80 (B7-1) and CD86 (B7-2), CD28 acts as the second signal for T and NK cell activation and proliferation. The 37.51 antibody has been reported to augmentin vitroT cell proliferation and cytokine production, and promote CTL development.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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