Brilliant Violet 421 anti-mouse CD34 Antibody anti-CD34 - SA376A4,BioLegend,152208
This antibody (clone SA376A4) is useful for staining mouse CD34+hematopoietic stem cell but it does not stain NIH-3T3 cells and the staining of Bend.3 cells is dimmer compared to other mouse CD34 antibodies, probably due to this antibody recognizes a different epitope than the other monoclonal antibodies.
Host
Rat
Reactivity
Mouse
Application
FC - Quality tested
Platform ID
BAB514798509
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NameBrilliant Violet 421 anti-mouse CD34 Antibody anti-CD34 - SA376A4
Cat. No.152208
HostRat
RRIDAB_2650765 (BioLegend Cat. No. 152207)AB_2650766 (BioLegend Cat. No. 152208)
IsotypeRat IgG2a, λ
ReactivityMouse
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberSA376A4
Concentration0.2 mg/ml
TargetCD34
ImmunogenMouse CD34 transfected cells.
PurityThe antibody was purified by affinity chromatography and conjugated with Brilliant Violet 421™ under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA).
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD34, also known as gp105-120, is a highly glycosylated type I monomeric sialomucin-like glycophophoprotein with an approximate molecular weight of 105-120 kD, with two generated by alternative splicing. CD34 is expressed on hematopoietic progenitors, endothelial cells, brain, and testis. CD34 mediates cell adhesion and lymphocytes homing through binding to L-selectin and E-selectin ligands, and mediates the attachment of stem cells to the extracellular matrix or stromal cells. CD34 is phosphorylated on serine residues by PKC.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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