Brilliant Violet 421™ anti-mouse MERTK (Mer) Antibody, MERTK (Mer), 2B10C42,BioLegend,151510
Host
Rat
Reactivity
Mouse
Application
FC -Quality tested
Platform ID
BAB731839337
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NameBrilliant Violet 421™ anti-mouse MERTK (Mer) Antibody, MERTK (Mer), 2B10C42
Cat. No.151510
HostRat
RRIDAB_2832533 (BioLegend Cat. No. 151510)
IsotypeRat IgG2a, κ
ReactivityMouse
ApplicationFC -Quality tested
ClonalityMonoclonal
Clone Number2B10C42
Concentration0.2 mg/mL
TargetMERTK
ImmunogenMouse MERTK extracellular domain
PurityThe antibody was purified by affinity chromatography and conjugated with Brilliant Violet 421™ under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
MerTK (Mer) is a member of the TAM (TYRO3/AXL/MerTK) family. It is a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type domains, and one tyrosine kinase domain. MerTK is mainly expressed by macrophages, monocytes, and dendritic cells. Its ligands are LGALS3, TUB, TULP1, and GAS6. MerTK is involved in the regulation of TLR signaling, efferocytosis, phagocytosis, cell survival, macrophage migration, and the inhibition of inflammation.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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