Brilliant Violet 510 anti-human CD1d Antibody anti-CD1d - 51.1,BioLegend,350314

Additional reported application (for the relevant formats) include: immunohistochemical staining of frozen tissue sections1, Western blotting1,2, and induction of IL-12 production by crosslinking of CD1d3.

Host

Mouse

Reactivity

Human

Application

FC - Quality tested

Platform ID

BAB126040145

BioLegend

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Contact

Tel: 1-858-455-9588
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Product Specifications
Scientific Background

Specifications

NameBrilliant Violet 510 anti-human CD1d Antibody anti-CD1d - 51.1
Cat. No.350314
HostMouse
RRIDAB_2563190 (BioLegend Cat. No. 350314)
IsotypeMouse IgG2b, κ
ReactivityHuman
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone Number51.1
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetCD1d
ImmunogenHuman CD1d-Fc fusion
PurityThe antibody was purified by affinity chromatography and conjugated with Brilliant Violet 510™ under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA).
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

CD1d is a MHC-like, type I transmembrane protein, member of the CD1 family and the immunoglobulin superfamily. On the cell surface, CD1d forms a heterodimer with β2-microglobulin. CD1d is expressed by antigen-presenting cells such as B cells, monocytes/macrophages, dendritic cells, and some non-lymphoid cells. Cortical thymocytes express CD1d but the expression is lost in mature T cells. CD1d presents lipid antigens toiNKT cells analogous to MHC molecule presentation of peptides to T cells.

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