Brilliant Violet 510™ anti-human CD27 Antibody, CD27, S20020G,BioLegend,384905
Clone S20020G is able to completely block the binding of clones M-T271 and O323 on target cells. Clone S20020G does not block binding of clone S20020H on target cells.
Host
Mouse
Reactivity
Human
Application
FC - Quality tested
Platform ID
BAB948469098
BioLegend
Contact
Tel: 1-858-455-9588
Fax: +49 (4131) 7023913
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Product Specifications
Scientific Background
Specifications
NameBrilliant Violet 510™ anti-human CD27 Antibody, CD27, S20020G
Cat. No.384905
HostMouse
RRIDAB_3068122 (BioLegend Cat. No. 384905)AB_3068122 (BioLegend Cat. No. 384906)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberS20020G
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetCD27
ImmunogenHu CD27 transfected cells
PurityThe antibody was purified by affinity chromatography and conjugated with Brilliant Violet 510™ under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD27, also known as S152 and T14, is a 50-55 kD type I membrane protein. It is a lymphocyte-specific member of the TNF-receptor superfamily. CD27 is expressed on medullary thymocytes, virtually all mature T cells, some B cells, and NK cells. CD27 binds to CD70 and plays an important role in costimulation of T cell activation, and regulation of B cell differentiation and proliferation. The cytoplasmic domains of CD27 have also been shown to interact with TRAF2 and TRAF5 to elicit NF-κB and SAPK/JNK activation.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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