Brilliant Violet 510™ anti-mouse/human Ki-67 Antibody, Ki-67, 11F6,BioLegend,151225
Host
Rat
Reactivity
Mouse, Human
Application
ICFC - Quality tested
Platform ID
BAB417034194
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NameBrilliant Violet 510™ anti-mouse/human Ki-67 Antibody, Ki-67, 11F6
Cat. No.151225
HostRat
RRIDAB_2941433 (BioLegend Cat. No. 151225)
IsotypeRat IgG2b, κ
ReactivityMouse, Human
ApplicationICFC - Quality tested
ClonalityMonoclonal
Clone Number11F6
Concentration0.2 mg/mL
TargetKi-67
ImmunogenE. coliexpressed, N-terminal His-Thioredoxin-tagged, partial mKi-67 (1816-2163 aa) recombinant protein.
PurityThe antibody was purified by affinity chromatography and conjugated with Brilliant Violet 510™ under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
The nuclear protein Ki-67 was first identified by the monoclonal antibody Ki-67, which was generated by immunizing mice with nuclei of the L428 Hodgkin lymphoma cell line. Ki-67 protein plays an essential role in ribosomal RNA transcription and cell proliferation. Expression of Ki-67 occurs during G1, S, G2, and M phase. While in G0 phase, the Ki-67 protein is not detectable. Ki-67 is strongly expressed in proliferating cells and has been reported as a prognostic marker in various tumors.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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