Brilliant Violet 605™ anti-human HLA-E Antibody, HLA-E, 3D12,BioLegend,342626

Host

Mouse

Reactivity

Human

Application

FC - Quality tested

Platform ID

BAB057961574

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

Email:

Product Specifications
Scientific Background

Specifications

NameBrilliant Violet 605™ anti-human HLA-E Antibody, HLA-E, 3D12
Cat. No.342626
HostMouse
RRIDAB_3097230 (BioLegend Cat. No. 342625)AB_3097230 (BioLegend Cat. No. 342626)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone Number3D12
ConcentrationLot-specific (to obtain lot-specific concentration, please enter the lot number in ourConcentration and Expiration LookuporCertificate of Analysisonline tools.)
TargetHLA-E
PurityThe antibody was purified by affinity chromatography and conjugated with Brilliant Violet 605™ under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

HLA-E is a non-classical MHC class I (MHC-Ib) molecule. It is characterized by limited polymorphism and ubiquitous expression. HLA-E, as other MHC-I molecules, is heterodimerized with β2-microglobulin. HLA-E interacts with CD94/NKG2 receptor to regulate NK cell cytolysis activities.

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