Brilliant Violet 650 anti-human CD137 4-1BB Antibody anti-CD137 - 4B4-1,BioLegend,309827
Additional reported applications (for the relevant formats) include: immunoprecipitation1,4, inhibition of cytokine production2,3, and ELISA. For most successful immunofluorescent staining results, it may be important to maximize signal over background by using a relatively bright fluorochrome-antibody conjugate (Cat. No. 309804) or by using a high sensitivity, three-layer staining technique (e.g., including a biotinylated anti-mouse IgG second step (Cat. No. 405303), followed by Streptavidin-PE (Cat. No. 405204)).
Host
Mouse
Reactivity
Human
Application
FC - Quality tested
Platform ID
BAB685972628
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NameBrilliant Violet 650 anti-human CD137 4-1BB Antibody anti-CD137 - 4B4-1
Cat. No.309827
HostMouse
RRIDAB_2572192 (BioLegend Cat. No. 309827)AB_2572193 (BioLegend Cat. No. 309828)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone Number4B4-1
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetCD137
ImmunogenEctodomain of recombinant human 4-1BB fusion protein
PurityThe antibody was purified by affinity chromatography and conjugated with Brilliant Violet 650™ under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA).
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD137 is a 39 kD transmembrane protein also known as 4-1BB. It is expressed on activated T cells. CD137 is a type I membrane protein and a member of the tumor necrosis factor receptor superfamily. CD137 appears to be important for T cell proliferation and survival, and induces monocyte activation through its interaction with 4-1BB ligand.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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