Brilliant Violet 650™ anti-human CD352 (NTB-A) Antibody, CD352, W19035D,BioLegend,332309

Host

Rat

Reactivity

Human

Application

FC - Quality tested

Platform ID

BAB082827104

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

BioLegend

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

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Product Specifications
Scientific Background

Specifications

NameBrilliant Violet 650™ anti-human CD352 (NTB-A) Antibody, CD352, W19035D
Cat. No.332309
HostRat
RRIDAB_3698984 (BioLegend Cat. No. 332309)AB_3698984 (BioLegend Cat. No. 332310)
IsotypeRat IgG2a, κ
ReactivityHuman
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberW19035D
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetCD352
ImmunogenRecombinant human CD352 protein
PurityThe antibody was purified by affinity chromatography and conjugated with Brilliant Violet 650™ under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

NTBA (NK-, T-, and B-cell Antigen) is a 60 kD type I transmembrane glycoprotein. It is a member of Ig superfamily belonging to CD2/CD150 subfamily, also known as SLAMF6 (SLAM family member 6), LY108, TCOM, or SF2000. This antigen is expressed on NK cells, T cells (upregulated upon activation), and B cells. NTBA is its own ligand. The homophilic interaction of NTBA is involved in the induction of NK cytotoxicity, CD28 independent T cell costimulation, triggering Th1 cytokines production, and regulation of B cell tolerance. It may play a role in the regulation of autoimmune diseases.

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