Brilliant Violet 650 anti-human CX3CR1 Antibody anti-CX3RCR1 - 2A9-1,BioLegend,341625

Host

Rat

Reactivity

Human

Application

FC -Quality tested

Platform ID

BAB988283771

BioLegend

Headquarters

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Contact

Tel: 1-858-455-9588
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Product Specifications
Scientific Background

Specifications

NameBrilliant Violet 650 anti-human CX3CR1 Antibody anti-CX3RCR1 - 2A9-1
Cat. No.341625
HostRat
RRIDAB_2716244 (BioLegend Cat. No. 341625)AB_2716245 (BioLegend Cat. No. 341626)
IsotypeRat IgG2b, κ
ReactivityHuman
ApplicationFC -Quality tested
ClonalityMonoclonal
Clone Number2A9-1
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetCX3CR1
ImmunogenCX3CR1-EGFP fusion protein
PurityThe antibody was purified by affinity chromatography and conjugated with Brilliant Violet 650™ under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA).
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

CX3CR1 is a G-protein-coupled seven-transmembrane chemokine receptor, also called GPR13 or V28. It is expressed on NK cells, T cell subset, monocytes/macrophages, dendritic cells, and some malignant epithelial cells. CX3CL1 (known also as fractalkine and neurotactin) is the ligand of CX3CR1. CX3CL1 is a unique transmembrane molecule with a CX3C-motif chemokine domain and a mucin-like stalk. CX3CL1 is expressed by activated-endothelial cells, neurons, and astrocytes. The interaction of CX3CR1 and its ligand mediatesfirm cell adhesion and migration.

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