Brilliant Violet 750™ anti-mouse CD11c Antibody CD11c, N418,BioLegend,117357
Additional reported applications (for the relevant formats) include: immunoprecipitation3, immunohistochemical staining of acetone-fixed frozen sections3, immunofluorescence microscopy5, 9(Alexa Fluor® 488 conjugated N418 was used for IHC in frozen sections10), and spatial biology (IBEX)22,23.
Host
Armenian Hamster
Reactivity
Mouse
Application
FC -Quality tested
Platform ID
BAB634174974

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Product Specifications
Scientific Background
Specifications
NameBrilliant Violet 750™ anti-mouse CD11c Antibody CD11c, N418
Cat. No.117357
HostArmenian Hamster
RRIDAB_2810351 (BioLegend Cat. No. 117357)
IsotypeArmenian Hamster IgG
ReactivityMouse
ApplicationFC -Quality tested
ClonalityMonoclonal
Clone NumberN418
Concentration0.2 mg/ml
TargetCD11c
ImmunogenMouse spleen dendritic cells
PurityThe antibody was purified by affinity chromatography and conjugated with Brilliant Violet 750™ under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA).
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD11c is a 150 kD glycoprotein also known as αXintegrin, CR4, and p150. CD11c forms a αXβ2heterodimer with β2integrin (CD18). It is primarily expressed on dendritic cells, NK cells, a subset of intestinal intraepithelial lymphocytes (IEL), and some activated T cells. The αXβ2integrin plays an important role in cell-cell contact by binding its ligands: iC3b, fibrinogen, and CD54.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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