Brilliant Violet 785 anti-human CD146 Antibody, CD146, P1H12,BioLegend,361030
Additional reported applications (for the relevant formats of this clone) include: Western blotting3and IHC1,5.Clone P1H12 cross-reacts to Dog2, 5.
Host
Mouse
Reactivity
Human
Application
FC -Quality tested
Platform ID
BAB389347490
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NameBrilliant Violet 785 anti-human CD146 Antibody, CD146, P1H12
Cat. No.361030
HostMouse
RRIDAB_2800995 (BioLegend Cat. No. 361029)AB_2800996 (BioLegend Cat. No. 361030)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationFC -Quality tested
ClonalityMonoclonal
Clone NumberP1H12
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetCD146
ImmunogenCultured human umbilical cells
PurityThe antibody was purified by affinity chromatography and conjugated with Brilliant Violet 785™ under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA).
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD146 is a 118 kD integral transmembrane glycoprotein that is also known as MUC18, S-Endo, MCAM, and Mel-CAM (melanoma cell adhesion molecule). It belongs to the immunoglobulin superfamily. CD146 is expressed on melanoma cells, epithelial cells, endothelial cells, fibroblasts, activated T cells, multipotent mesenchymal stromal cells, and activated keratinocytes. CD146 mediates heterophilic cell adhesion and regulates monocyte transendothelial migration. The ligand of CD146 remains to be identified.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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