Bulk Anti-Human CD2 (LO-CD2a) In Vivo Antibody,ichor.bio,ICH1193

Anti-CD2 antibody (clone LO-CD2a) activity is directed against human CD2.

Host

Rat

Reactivity

Human

Platform ID

BAB572158319

ichor.bio

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Grove Business Park Downsview Road Wantage OX12 9FF

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Product Specifications
Scientific Background
Synonyms

Specifications

NameBulk Anti-Human CD2 (LO-CD2a) In Vivo Antibody
Cat. No.ICH1193
HostRat
IsotypeRat IgG2b Kappa
ReactivityHuman
Clone NumberLO-CD2a
Concentration≤ 2.0 mg/ml
TargetCD2
ImmunogenLO-CD2a was developed as an immunosuppressive agent for use in organ allotransplantation. LO-CD2a was produced by immunizing a LOU/C rat with purified human T lymphocytes and fusing the splenocytes with the non-secreting rat fusion cell line IR983F, resul
Purity>95% by SDS-PAGE
Endotoxin Level<1.0 EU/mg as determined by the LAL method
ShippingBlue ice
FormulationICH3001-100ml ICH3002-100ml ICH3003-100ml
StorageThis antibody is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.
Regulatory StatusFor research use only

Scientific Background

LO-CD2a strongly inhibits mixed lymphocyte culture (MLC) 3 and induces T cell apoptosis. Additionally, LO-CD2a does not induce proliferation of resting T cells, and inhibits T cell proliferation induced by OKT3 antibody, induces very low levels of cytokin

Synonyms

BTI-322, CD2, CD2 molecule, T11, SRBC, LFA-2, T-cell surface antigen CD2, LFA-3 receptor, rosette receptor, erythrocyte receptor, lymphocyte-function antigen-2, T-cell surface antigen T11/Leu-5, CD2 antigen (p50), sheep red blood cell receptor

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