Bulk anti-Human CXCR4 (12G5) Antibody,ichor.bio,ICH1199

12G5 activity is directed against human CXCR4 (CD184; Fusin)

Host

Mouse

Reactivity

Human

Platform ID

BAB634739530

ichor.bio

Headquarters

Grove Business Park Downsview Road Wantage OX12 9FF

Contact

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Product Specifications
Scientific Background
Synonyms

Specifications

NameBulk anti-Human CXCR4 (12G5) Antibody
Cat. No.ICH1199
HostMouse
IsotypeMouse IgG2a Kappa
ReactivityHuman
Clone Number12G5
Concentration≤ 2.0 mg/ml
TargetCXCR4
Immunogen12G5 was produced by immunizing Balb/c mice with CP-MAC-infected Sup-T1 cells. Hybridomas were generated and screened for the ability to inhibit CP-MAC-induced syncytium induction on Sup-T1 cells.
Purity>95% by SDS-PAGE
Endotoxin Level<1.0 EU/mg as determined by the LAL method
ShippingBlue ice
FormulationICH3001-100ml ICH3002-100ml ICH3003-100ml
StorageThis antibody is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.
Regulatory StatusFor research use only

Scientific Background

12G5 binds specifically to both human and nonhuman cells that express recombinant CXCR4. 12G5 inhibits CD4-independent infection by some HIV-2 isolates, and preincubating cells with 12G5 abolishes syncytium formation. HIV-2/vcp-infected cells display a ma

Synonyms

Fusin, LESTR, CD184

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