C-C Motif Chemokine 2 / MCP1 (CCL2) Antibody,Abbexa,abx032942

Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. CCL2 is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4.

Host

Rabbit

Reactivity

Human

Application

ELISA, WB, IHC, IF/ICC, FCM

Conjugate

Unconjugated

Platform ID

BAB271962943

Abbexa

Headquarters

181 Cambridge Science Park Cambridge, CB4 0GJ United Kingdom

Contact

Tel: +44 (0) 1223 755950
Fax: +44 (0) 1223 755951

Product Specifications

Specifications

NameC-C Motif Chemokine 2 / MCP1 (CCL2) Antibody
Cat. No.abx032942
Accession NumberP13500
Gene ID (Entrez)6347
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationELISA, WB, IHC, IF/ICC, FCM
Working DilutionsWB: 1/1000, IHC-P: 1/10 - 1/50, IF/ICC: 1/10 - 1/50, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
ClonalityPolyclonal
Molecular WeightCalculated MW: 11 kDa
TargetCCL2
ImmunogenKLH-conjugated synthetic peptide between 62-89 amino acids from the C-terminal region of human CCL2.
PurityPurified Rabbit Polyclonal Antibody.
Appearance/FormLiquid
FormulationPBS containing 0.09% sodium azide.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Regulatory StatusResearch Use Only

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