C-Peptide (E7U7F) Rabbit Monoclonal Antibody#38069,Cell Signaling Technology (CST),38069

C-Peptide (E7U7F) Rabbit Monoclonal Antibody recognizes endogenous levels of total C-peptide protein.

Host

Rabbit

Reactivity

Human

Application

Immunohistochemistry (Paraffin): 1:50 - 1:200

Platform ID

BAB216962688

Cell Signaling Technology (CST)

Headquarters

3 Trask Lane Danvers, MA 01923

Cell Signaling Technology (CST)

Contact

Tel: 877-616-2355,978-867-2388
Fax: 877-616-2355

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameC-Peptide (E7U7F) Rabbit Monoclonal Antibody#38069
Cat. No.38069
Accession NumberP01308
Gene ID (Entrez)01308, 3630
HostRabbit
SensitivityEndogenous
ReactivityHuman
ApplicationImmunohistochemistry (Paraffin): 1:50 - 1:200
ImmunogenIgG
FormulationSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at –20°C.Do not aliquot the antibody.For a carrier free (BSA and azide free) version of this product see product #45404.
StorageSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at –20°C.Do not aliquot the antibody.For a carrier free (BSA and azide free) version of this product see product #45404.
Regulatory StatusResearch Use Only

Scientific Background

Glucose homeostasis is regulated by hormones. Elevation of blood glucose levels during feeding stimulates insulin release from pancreatic β-cells through a glucose sensing pathway (1). Proinsulin, the insulin precursor molecule, is processed prior to its secretion. Insulin is composed of A-peptide and B-peptide which are joined by a disulfide bond. The center one-third of the molecule is cleaved and released as C-peptide, which has a longer half-life than insulin (2).Straub, S.G. and Sharp, G.W. (2002)Diabetes Metab. Res. Rev.18, 451-463.Polonsky, K.S. and Rubenstein, A.H. (1984)Diabetes33, 486-494.Alternate NamesIDDM; IDDM1; IDDM2; ILPR; ins; Insulin; insulin (A chain, B chain); Insulin A chain; Insulin B chain; IRDN; MODY10; PNDM4; preproinsulin; proinsulin

Synonyms

IDDM; IDDM1; IDDM2; ILPR; ins; Insulin; insulin (A chain, B chain); Insulin A chain; Insulin B chain; IRDN; MODY10; PNDM4; preproinsulin; proinsulin

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