C-Peptide antibody [GT1455],Genetex,GTX631941

Host

Mouse

Reactivity

Human

Application

ELISA

Conjugate

Unconjugated

Platform ID

BAB082472332

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameC-Peptide antibody [GT1455]
Cat. No.GTX631941
HostMouse
IsotypeIgG2b
ReactivityHuman
ConjugationUnconjugated
ApplicationELISA
ClonalityMonoclonal
Concentration1.82 mg/ml (Please refer to the vial label for the specific concentration.)
ImmunogenCarrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human C-Peptide. The exact sequence is proprietary.
PurityAffinity purified by Protein A.
Appearance/FormLiquid
FormulationPBS,No preservatives
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into two chains (peptide A and peptide B) that are covalently linked via two disulfide bonds. Binding of this mature form of insulin to the insulin receptor (INSR) stimulates glucose uptake. A variety of mutant alleles with changes in the coding region have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. [provided by RefSeq]

Synonyms

INS Antibody , insulin Antibody , IRDN Antibody , IDDM2 Antibody , MODY10 Antibody , ILPR Antibody

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