C1orf187/Draxin Polyclonal Antibody,Bioss,bs-9220R

Host

Rabbit

Reactivity

Human, Mouse, Rat

Application

WB, ELISA, IHC-P, IHC-F, IF

Conjugate

Unconjugated

Platform ID

BAB814664389

Bioss

Headquarters

300 Tradecenter Dr, ste 4610Woburn, Massachusetts 01801 - U.S.A.

Contact

Tel: +1.781.569.5821
Fax: +1.781.731.9286

Product Specifications
Scientific Background
Synonyms

Specifications

NameC1orf187/Draxin Polyclonal Antibody
Cat. No.bs-9220R
Gene ID (Entrez)374946
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB, ELISA, IHC-P, IHC-F, IF
Working DilutionsWB:1:300-5000 | ELISA:IHC-P1:200-400 | IHC-P:IFIHC-P1:50-200 | IHC-F: | IF:
ClonalityPolyclonal
Concentration1ug/ul
PurityPurified by Protein A.
Formulation0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
StorageShipped at 4_. Store at -20_ for one year. Avoid repeated freeze/thaw cycles.

Scientific Background

Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway.

Synonyms

AGPA3119; C1orf187; Chromosome 1 open reading frame 187; Dorsal repulsive axon guidance protein; DRAXI_HUMAN; Draxin; Neucrin; UNQ3119.

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