C5aR, Human, mAb W17/1,Hycult Biotech,HM2095

The human anaphylatoxin C5a is a 74-residu glycopolypeptide which is generated by proteolytic cleavage of the complement factor C5 in the course of complement activation. A variety of biological effects evoked by C5a could be demonstrated, rendering this molecule an important mediator of inflammation, with granulocytes and macrophages as the main target cells. All cellular responses to C5a are specifically mediated by interactions with the membrane bound C5a receptor, a seven transmembrane GTP-binding-protein-coupled receptor that belongs to the rhodopsin supergene family. The C5a receptor is approximately 45 kDa.

Host

Human

Platform ID

BAB758616593

Hycult Biotech

Headquarters

Frontstraat 2a 5405 PB Uden, The Netherlands

Contact

Tel: +31 (0)413 251335
Fax: +31(0)413 248353

Product Specifications

Specifications

NameC5aR, Human, mAb W17/1
Cat. No.HM2095
HostHuman
IsotypeMouse IgG1
Formulation0.2 ml (100 µg/ml) 0.2 µm filtered antibody solution in PBS, containing 0.1% bovine serum albumin and 0.02 % sodium azide.
StorageProduct should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.
Regulatory StatusResearch Use Only

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