CD11b, Human, mAb Bear-1,Hycult Biotech,HM2125

Name: CD11b, Human, mAb Bear-1,Hycult Biotech,HM2125
Brand: Buy Antibody
SKU: BAB258766521

CD11b is an alpha chain integrin that is expressed as heterodimer noncovalently associated with CD18. CD11b is also designated as CR3, Mac-1, Mo-1 in integrin alphaM subunit and has a molecular weight of 165-170 kDa. The protein mediates PMN and monocytes adherence to endothelium and subsequently PMN extravasation to sites of inflammation. CD11b/CD18 interacts with both matrix and cell surface proteins including the complement component iC3b, extracellular matrix proteins and the third extracellular domain of CD54. CD11b is expressed on human NK-cells, monocytes, granulocytes, T-cells, B-cells and dendritic cells. After activation the expression is upregulated. Bear-1 reacts with the CD11b alpha chain of the CD11b/CD18 (p165, 95) integrin heterodimer complex.

Host

Human

Platform ID

BAB258766521

Frontstraat 2a 5405 PB Uden, The Netherlands

Tel: +31 (0)413 251335
Fax: +31(0)413 248353

Product Specifications

NameCD11b, Human, mAb Bear-1

Cat. No.HM2125

HostHuman

IsotypeMouse IgG1

Formulation0.2 ml (100 µg/ml) 0.2 µm filtered antibody solution in PBS, containing 0.02% sodium azide and 0.1% bovine serum albumin.

StorageProduct should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.

Regulatory StatusResearch Use Only

Request a product

Please provide the required information below so that we can quickly source your products.