CD11c Rabbit PolymAb®,ABclonal,A28244PM

Reactivity

Human, Cynomolgus monkey

Application

WB, IF-P, IHC-P, ELISA

Conjugate

Unconjugated

Platform ID

BAB189087339

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

Contact

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Product Specifications
Scientific Background

Specifications

NameCD11c Rabbit PolymAb®
Cat. No.A28244PM
RRID#N/A
IsotypeIgG
ReactivityHuman, Cynomolgus monkey
ConjugationUnconjugated
ApplicationWB, IF-P, IHC-P, ELISA
Working DilutionsWB:1:5000 - 1:10000 | IF/ICC:1:200 - 1:400 | IHC-P:1:2000 - 1:8000 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements. For high-ratio antibody dilutions (≥1:10000),a sequential dilution method is strongly recommended to ensure measurement accuracy.
Molecular Weight145 kDa
ImmunogenSynthetic peptide. This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS with 0.09% Sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. Two transcript variants encoding different isoforms have been found for this gene.

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